Synthesis of polymeric Janus superstructures via a facile synthesis method

Synthesis of polymeric Janus superstructures via a facile synthesis method

Polymeric Janus particles can be exploited for a myriad of applications. Through the understanding of interfacial tensions, theragnostic agents such as drugs or nanomaterials can be successfully encapsulated into Janus particles without losing their anisotropic structure. In this work, it is reporte...

Full description

Saved in:
Bibliographic Details
Main Authors: Lim, Jerome Yi Guang, Low, Jessalyn Hui Ying, Loo, Joachim Say Chye
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2020
Subjects:
Engineering::Materials
Drug Delivery Systems
Emulsion
Online Access:https://hdl.handle.net/10356/144490
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-144490
record_format dspace
spelling sg-ntu-dr.10356-1444902023-07-14T16:00:13Z Synthesis of polymeric Janus superstructures via a facile synthesis method Lim, Jerome Yi Guang Low, Jessalyn Hui Ying Loo, Joachim Say Chye School of Materials Science and Engineering Singapore Centre for Environmental Life Sciences and Engineering Engineering::Materials Drug Delivery Systems Emulsion Polymeric Janus particles can be exploited for a myriad of applications. Through the understanding of interfacial tensions, theragnostic agents such as drugs or nanomaterials can be successfully encapsulated into Janus particles without losing their anisotropic structure. In this work, it is reported that how Janus superstructures, as a further extension of the Janus morphology, can be obtained by blending other synthesis parameters into the solvent emulsion process, while adhering to the requirements of the Harkin's spreading coefficient (HSC) theory. Designing such unique structures for drug delivery can provide a broader range of possibilities and applications beyond conventional Janus particles. Ministry of Education (MOE) Accepted version The authors would like to acknowledge the financial support from the Singapore Centre for Environmental Life Sciences Engineering (SCELSE) (MOE/RCE: M4330019.C70), Ministry of Education AcRF grant (RG19/18 & RT08/19), Agri-Food & Veterinary Authority of Singapore (APF LCK102), Biomedical Research Council (BMRC) – Therapeutics Development Review (TDR-G-004-001), NTU-HSPH grant (NTU-HSPH 17002), and the Bill and Melinda Gates Foundation (OPP1199116). 2020-11-09T02:33:36Z 2020-11-09T02:33:36Z 2020 Journal Article Lim, J. Y. G., Low, Jessalyn H. Y., & Loo, J. S. C. (2020). Synthesis of polymeric Janus superstructures via a facile synthesis method. Macromolecular Rapid Communications, 41(21), 2000140-. doi:10.1002/marc.202000140 1022-1336 https://hdl.handle.net/10356/144490 10.1002/marc.202000140 21 41 2000140 en Macromolecular Rapid Communications This is the accepted version of the following article: Lim, J. Y. G., Low, Jessalyn H. Y., & Loo, J. S. C. (2020). Synthesis of polymeric Janus superstructures via a facile synthesis method. Macromolecular Rapid Communications, 41(21), 2000140-. doi:10.1002/marc.202000140, which has been published in final form at 10.1002/marc.202000140. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/authorresources/Journal-Authors/licensing/self-archiving.html]. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Materials
Drug Delivery Systems
Emulsion
spellingShingle Engineering::Materials
Drug Delivery Systems
Emulsion
Lim, Jerome Yi Guang
Low, Jessalyn Hui Ying
Loo, Joachim Say Chye
Synthesis of polymeric Janus superstructures via a facile synthesis method
description Polymeric Janus particles can be exploited for a myriad of applications. Through the understanding of interfacial tensions, theragnostic agents such as drugs or nanomaterials can be successfully encapsulated into Janus particles without losing their anisotropic structure. In this work, it is reported that how Janus superstructures, as a further extension of the Janus morphology, can be obtained by blending other synthesis parameters into the solvent emulsion process, while adhering to the requirements of the Harkin's spreading coefficient (HSC) theory. Designing such unique structures for drug delivery can provide a broader range of possibilities and applications beyond conventional Janus particles.
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Lim, Jerome Yi Guang
Low, Jessalyn Hui Ying
Loo, Joachim Say Chye
format Article
author Lim, Jerome Yi Guang
Low, Jessalyn Hui Ying
Loo, Joachim Say Chye
author_sort Lim, Jerome Yi Guang
title Synthesis of polymeric Janus superstructures via a facile synthesis method
title_short Synthesis of polymeric Janus superstructures via a facile synthesis method
title_full Synthesis of polymeric Janus superstructures via a facile synthesis method
title_fullStr Synthesis of polymeric Janus superstructures via a facile synthesis method
title_full_unstemmed Synthesis of polymeric Janus superstructures via a facile synthesis method
title_sort synthesis of polymeric janus superstructures via a facile synthesis method
publishDate 2020
url https://hdl.handle.net/10356/144490
_version_ 1773551198696112128

Similar Items