Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes

• Main Authors: Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Escolà-Gil, Joan Carles, Cedó, Lidia, Wahli, Walter, Vázquez-Carrera, Manuel
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Very Low-density Lipoprotein Receptor; Non-alcoholic Fatty Liver Disease
• Online Access: https://hdl.handle.net/10356/144815
• Institution: Nanyang Technological University

The very low-density lipoprotein receptor (VLDLR) plays an important function in the control of serum triglycerides and in the development of non-alcoholic fatty liver disease (NAFLD). In this study, we investigated the role of peroxisome proliferator-activated receptor (PPAR)β/δ activation in hepat...