GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) activates AMP-activated protein kinase (AMPK) and plays a crucial role in glucose and lipid metabolism. Here, we examine whether PPARβ/δ activation effects depend on growth differentiation factor 15 (GDF15), a stress response cytokine that reg...

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Bibliographic Details
Main Authors: Aguilar-Recarte, David, Barroso, Emma, Gumà, Anna, Pizarro-Delgado, Javier, Peña, Lucía, Ruart, Maria, Palomer, Xavier, Wahli, Walter, Vázquez-Carrera, Manuel
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
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Online Access:https://hdl.handle.net/10356/153809
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Institution: Nanyang Technological University
Language: English