Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis

• Main Authors: Chandrashekar, Preeti, Manickam, Ravikumar, Ge, Xiaojia, Bonala, Sabeera, McFarlane, Craig, Sharma, Mridula, Wahli, Walter, Kambadur, Ravi
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Myostatin; PPARβ/δ; Skeletal muscle regeneration
• Online Access: https://hdl.handle.net/10356/81571; http://hdl.handle.net/10220/39597
• Institution: Nanyang Technological University

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a ubiquitously expressed gene with higher levels observed in skeletal muscle. Recently, our laboratory showed (Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. J Biol Chem 287: 12935–12951, 2012) that PP...