Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1

• Main Authors: Traczyk, Anna, Liew, Chong Wai, Gill, David James, Rhodes, Daniela
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; DNA; Guanine Quadruplex
• Online Access: https://hdl.handle.net/10356/145061
• Institution: Nanyang Technological University

G-quadruplexes are four-stranded nucleic acid structures involved in multiple cellular pathways including DNA replication and telomere maintenance. Such structures are formed by G-rich DNA sequences typified by telomeric DNA repeats. Whilst there is evidence for proteins that bind and regulate G-qua...