Rotation of Guanine Amino Groups in G-Quadruplexes: A Probe for Local Structure and Ligand Binding

• Main Authors: Adrian, Michael, Winnerdy, Fernaldo Richtia, Heddi, Brahim, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: DNA; Guanine
• Online Access: https://hdl.handle.net/10356/86336; http://hdl.handle.net/10220/44018
• Institution: Nanyang Technological University

Nucleic acids are dynamic molecules whose functions may depend on their conformational fluctuations and local motions. In particular, amino groups are dynamic components of nucleic acids that participate in the formation of various secondary structures such as G-quadruplexes. Here, we present a cost...