Guanine base stacking in G-quadruplex nucleic acids

• Main Authors: Lech, Christopher Jacques, Heddi, Brahim, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Physics::Atomic physics::Quantum theory
• Online Access: https://hdl.handle.net/10356/97174; http://hdl.handle.net/10220/9983
• Institution: Nanyang Technological University

G-quadruplexes constitute a class of nucleic acid structures defined by stacked guanine tetrads (or G-tetrads) with guanine bases from neighboring tetrads stacking with one another within the G-tetrad core. Individual G-quadruplexes can also stack with one another at their G-tetrad interface leading...