High-resolution AFM structure of DNA G-wires in aqueous solution

We investigate the self-assembly of short pieces of the Tetrahymena telomeric DNA sequence d[G4T2G4] in physiologically relevant aqueous solution using atomic force microscopy (AFM). Wire-like structures (G-wires) of 3.0 nm height with well-defined surface periodic features were observed. Analysis o...

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Bibliographic Details
Main Authors: Bose, Krishnashish, Lech, Christopher Jacques, Heddi, Brahim, Phan, Anh Tuân
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2018
Subjects:
DNA
Online Access:https://hdl.handle.net/10356/87043
http://hdl.handle.net/10220/45293
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Institution: Nanyang Technological University
Language: English