High-resolution AFM structure of DNA G-wires in aqueous solution

• Main Authors: Bose, Krishnashish, Lech, Christopher Jacques, Heddi, Brahim, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Atomic Force Microscopy; DNA
• Online Access: https://hdl.handle.net/10356/87043; http://hdl.handle.net/10220/45293
• Institution: Nanyang Technological University

We investigate the self-assembly of short pieces of the Tetrahymena telomeric DNA sequence d[G4T2G4] in physiologically relevant aqueous solution using atomic force microscopy (AFM). Wire-like structures (G-wires) of 3.0 nm height with well-defined surface periodic features were observed. Analysis o...