Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines

• Main Authors: Ahmed Ibrahim Samir Khalil, Siti Rawaidah Mohammad Muzaki, Chattopadhyay, Anupam, Sanyal, Amartya
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Chromosome Conformation Capture; Hi-C Normalization Tool
• Online Access: https://hdl.handle.net/10356/145880
• Institution: Nanyang Technological University

Background: Hi-C and its variant techniques have been developed to capture the spatial organization of chromatin. Normalization of Hi-C contact map is essential for accurate modeling and interpretation of high-throughput chromatin conformation capture (3C) experiments. Hi-C correction tools were ori...