Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes

Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes

Background: Detection of DNA copy number alterations (CNAs) is critical to understand genetic diversity, genome evolution and pathological conditions such as cancer. Cancer genomes are plagued with widespread multi-level structural aberrations of chromosomes that pose challenges to discover CNAs of...

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Bibliographic Details
Main Authors: Ahmed Ibrahim Samir Khalil, Khyriem, Costerwell, Chattopadhyay, Anupam, Sanyal, Amartya
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2021
Subjects:
Engineering::Computer science and engineering
Cancer
DNA Copy Number Alteration
Online Access:https://hdl.handle.net/10356/146948
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/146948

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