Deep learning based DNA:RNA triplex forming potential prediction

• المؤلفون الرئيسيون: Zhang, Yu, Long, Yahui, Kwoh, Chee Keong
• مؤلفون آخرون: School of Computer Science and Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Biological sciences; Long Noncoding RNAs; DNA:RNA Triplex
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/145881
• المؤسسة: Nanyang Technological University

Background: Long non-coding RNAs (lncRNAs) can exert functions via forming triplex with DNA. The current methods in predicting the triplex formation mainly rely on mathematic statistic according to the base paring rules. However, these methods have two main limitations: (1) they identify a large num...