Deep learning based DNA:RNA triplex forming potential prediction

• Main Authors: Zhang, Yu, Long, Yahui, Kwoh, Chee Keong
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Long Noncoding RNAs; DNA:RNA Triplex
• Online Access: https://hdl.handle.net/10356/145881
• Institution: Nanyang Technological University

Background: Long non-coding RNAs (lncRNAs) can exert functions via forming triplex with DNA. The current methods in predicting the triplex formation mainly rely on mathematic statistic according to the base paring rules. However, these methods have two main limitations: (1) they identify a large num...