Defining the structural basis for human leukocyte antigen reactivity in clinical transplantation

• المؤلفون الرئيسيون: Gu, Yue, Koh, Robynne W. K., Lai, May Ling, Pochinco, Denise, Teo, Rachel Z. C., Chan, Marieta, Murali, Tanusya M., Liew, Chong Wai, Wong, Yee Hwa, Gascoigne, Nicholas R. J., Wood, Kathryn J., Lescar, Julien, Nickerson, Peter, MacAry, Paul A., Vathsala, Anantharaman
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Biological sciences; Immunology; Medical Research
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/146045

The current state-of-the-art technology employed to assess anti-human leukocyte antigen antibodies (Anti-HLA Ab) for donor-recipient matching and patient risk stratification in renal transplantation is the single antigen bead (SAB) assay. However, there are limitations to the SAB assay as it is not...