A non-viral genome editing platform for site-specific insertion of large transgenes

Background: The precise, functional and safe insertion of large DNA payloads into host genomes offers versatility in downstream genetic engineering-associated applications, spanning cell and gene therapies, therapeutic protein production, high-throughput cell-based drug screening and reporter cell l...

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Bibliographic Details
Main Authors: Chaudhari, Namrata, Rickard, Amanda M., Roy, Suki, Dröge, Peter, Makhija, Harshyaa
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/146047
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Institution: Nanyang Technological University
Language: English