How to do quantile normalization correctly for gene expression data analyses

Quantile normalization is an important normalization technique commonly used in high-dimensional data analysis. However, it is susceptible to class-effect proportion effects (the proportion of class-correlated variables in a dataset) and batch effects (the presence of potentially confounding technic...

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Bibliographic Details
Main Authors: Zhao, Yaxing, Wong, Limsoon, Goh, Wilson Wen Bin
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/146067
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Institution: Nanyang Technological University
Language: English