Cohort profile : the diet and healthy aging (DaHA) study in Singapore

How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-b...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu, Rongjun, Sun, Ye, Ye, Kaisy Xinhong, Feng, Qiushi, Lim, Su Lin, Mahendran, Rathi, Cheah, Irwin Kee-Mun, Foo, Roger Sik Yin, Chua, Ru Yuan, Gwee, Xinyi, Loh, Marie, Sarmugam, Rani, Khine, Wei Wei Thwe, Chao, Yin Xia, Larbi, Anis, Lee, Yuan Kun, Kumar, Alan Prem, Kennedy, Brian K., Kua, Ee-Heok, Feng, Lei
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/146159
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-146159
record_format dspace
spelling sg-ntu-dr.10356-1461592023-03-05T16:43:35Z Cohort profile : the diet and healthy aging (DaHA) study in Singapore Yu, Rongjun Sun, Ye Ye, Kaisy Xinhong Feng, Qiushi Lim, Su Lin Mahendran, Rathi Cheah, Irwin Kee-Mun Foo, Roger Sik Yin Chua, Ru Yuan Gwee, Xinyi Loh, Marie Sarmugam, Rani Khine, Wei Wei Thwe Chao, Yin Xia Larbi, Anis Lee, Yuan Kun Kumar, Alan Prem Kennedy, Brian K. Kua, Ee-Heok Feng, Lei Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Cognitive Impairment DaHA How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-based longitudinal study conducted to examine the role of diet and nutrition in promoting cognitive, emotional, and physical health among community-living elderly Singaporeans. The first wave of DaHA, conducted from 2011 to 2017, provided detailed information on diet and baseline cognitive function and health from 1010 community-living elderly in Singapore. Biomarkers of oxidative stress, systemic inflammation, and genetic information were collected. The ongoing second wave of DaHA is conducted from 2017 to 2020, which provides follow- up assessments using established cognitive tests and clinical tools. This well-characterized cohort, with its archived biological samples and high-quality data on diet and lifestyle factors will allow researchers to explore the relationships among diet, nutrition, genes, cognition, mental and physical health in an extremely cost-effective manner. Translations of the research findings into clinical and public health practices will potentially help to promote cognitive health at the population level and reduce healthcare costs related to cognitive impairment. National Medical Research Council (NMRC) Published version This work is supported by the following grants awarded to Dr Lei Feng: the National University of Singapore Virtual Institute for the Study of Ageing [grant number VG-8]; the Alice Lim Memorial Fund, Singapore [grant number ALMFA/2010]; the National Medical Research Council of Singapore [grant number NMRC/TA/ 0053/2016]. 2021-01-28T06:46:31Z 2021-01-28T06:46:31Z 2020 Journal Article Yu, R., Sun, Y., Ye, K. X., Feng, Q., Lim, S. L., Mahendran, R., . . . Feng, L. (2020). Cohort profile : the diet and healthy aging (DaHA) study in Singapore. Aging, 12(23), 23889-23899. doi:10.18632/aging.104051 1945-4589 https://hdl.handle.net/10356/146159 10.18632/aging.104051 33271510 2-s2.0-85098080717 23 12 23889 23899 en NMRC/TA/0053/2016 Aging © 2020 Yu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Cognitive Impairment
DaHA
spellingShingle Science::Medicine
Cognitive Impairment
DaHA
Yu, Rongjun
Sun, Ye
Ye, Kaisy Xinhong
Feng, Qiushi
Lim, Su Lin
Mahendran, Rathi
Cheah, Irwin Kee-Mun
Foo, Roger Sik Yin
Chua, Ru Yuan
Gwee, Xinyi
Loh, Marie
Sarmugam, Rani
Khine, Wei Wei Thwe
Chao, Yin Xia
Larbi, Anis
Lee, Yuan Kun
Kumar, Alan Prem
Kennedy, Brian K.
Kua, Ee-Heok
Feng, Lei
Cohort profile : the diet and healthy aging (DaHA) study in Singapore
description How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-based longitudinal study conducted to examine the role of diet and nutrition in promoting cognitive, emotional, and physical health among community-living elderly Singaporeans. The first wave of DaHA, conducted from 2011 to 2017, provided detailed information on diet and baseline cognitive function and health from 1010 community-living elderly in Singapore. Biomarkers of oxidative stress, systemic inflammation, and genetic information were collected. The ongoing second wave of DaHA is conducted from 2017 to 2020, which provides follow- up assessments using established cognitive tests and clinical tools. This well-characterized cohort, with its archived biological samples and high-quality data on diet and lifestyle factors will allow researchers to explore the relationships among diet, nutrition, genes, cognition, mental and physical health in an extremely cost-effective manner. Translations of the research findings into clinical and public health practices will potentially help to promote cognitive health at the population level and reduce healthcare costs related to cognitive impairment.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Yu, Rongjun
Sun, Ye
Ye, Kaisy Xinhong
Feng, Qiushi
Lim, Su Lin
Mahendran, Rathi
Cheah, Irwin Kee-Mun
Foo, Roger Sik Yin
Chua, Ru Yuan
Gwee, Xinyi
Loh, Marie
Sarmugam, Rani
Khine, Wei Wei Thwe
Chao, Yin Xia
Larbi, Anis
Lee, Yuan Kun
Kumar, Alan Prem
Kennedy, Brian K.
Kua, Ee-Heok
Feng, Lei
format Article
author Yu, Rongjun
Sun, Ye
Ye, Kaisy Xinhong
Feng, Qiushi
Lim, Su Lin
Mahendran, Rathi
Cheah, Irwin Kee-Mun
Foo, Roger Sik Yin
Chua, Ru Yuan
Gwee, Xinyi
Loh, Marie
Sarmugam, Rani
Khine, Wei Wei Thwe
Chao, Yin Xia
Larbi, Anis
Lee, Yuan Kun
Kumar, Alan Prem
Kennedy, Brian K.
Kua, Ee-Heok
Feng, Lei
author_sort Yu, Rongjun
title Cohort profile : the diet and healthy aging (DaHA) study in Singapore
title_short Cohort profile : the diet and healthy aging (DaHA) study in Singapore
title_full Cohort profile : the diet and healthy aging (DaHA) study in Singapore
title_fullStr Cohort profile : the diet and healthy aging (DaHA) study in Singapore
title_full_unstemmed Cohort profile : the diet and healthy aging (DaHA) study in Singapore
title_sort cohort profile : the diet and healthy aging (daha) study in singapore
publishDate 2021
url https://hdl.handle.net/10356/146159
_version_ 1759857249953513472