Structural analysis of SARS-CoV-2 genome and predictions of the human interactome

• Main Authors: Vandelli, Andrea, Monti, Michele, Milanetti, Edoardo, Armaos, Alexandros, Rupert, Jakob, Zacco, Elsa, Bechara, Elias, Ponti, Riccardo Delli, Tartaglia, Gian Gaetano
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2021
• 主題: Science::Biological sciences; ACE2 Protein; Coronavirus Spike Glycoprotein
• 在線閱讀: https://hdl.handle.net/10356/146330
• 機構: Nanyang Technological University

Specific elements of viral genomes regulate interactions within host cells. Here, we calculated the secondary structure content of >2000 coronaviruses and computed >100 000 human protein interactions with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The genomic regions display...