Design, synthesis and biological evaluation of novel anthraniloyl-amp mimics as PQS biosynthesis inhibitors against pseudomonas aeruginosa resistance

The Pseudomonas quinolone system (PQS) is one of the three major interconnected quorum sensing signaling systems in Pseudomonas aeruginosa. The virulence factors PQS and HHQ activate the transcription regulator PqsR (MvfR), which controls several activities in bacteria, including biofilm formation a...

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Bibliographic Details
Main Authors: Sabir, Shekh, Subramoni, Sujatha, Das, Theerthankar, Black, David StC, Rice, Scott A., Kumar, Naresh
Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/146344
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Institution: Nanyang Technological University
Language: English
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