Discovering putative protein targets of small molecules : a study of the p53 activator Nutlin

Discovering putative protein targets of small molecules : a study of the p53 activator Nutlin

Small molecule drugs bind to a pocket in disease causing target proteins based on complementarity in shape and physicochemical properties. There is a likelihood that other proteins could have binding sites that are structurally similar to the target protein. Binding to these other proteins could alt...

Full description

Saved in:
Bibliographic Details
Main Authors: Nguyen, Minh N., Sen, Neeladri, Lin, Meiyin, Joseph, Thomas Leonard, Vaz, Candida, Tanavde, Vivek, Way, Luke, Hupp, Ted, Verma, Chandra Shekhar, Madhusudhan, M. S.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
Nutlin
Binding-sites
Online Access:https://hdl.handle.net/10356/146761
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/146761

Similar Items