Discovering putative protein targets of small molecules : a study of the p53 activator Nutlin
Small molecule drugs bind to a pocket in disease causing target proteins based on complementarity in shape and physicochemical properties. There is a likelihood that other proteins could have binding sites that are structurally similar to the target protein. Binding to these other proteins could alt...
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Main Authors: | , , , , , , , , , |
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格式: | Article |
語言: | English |
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2021
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在線閱讀: | https://hdl.handle.net/10356/146761 |
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