RNA G-quadruplex structures mediate gene regulation in bacteria

• Main Authors: Shao, Xiaolong, Zhang, Weitong, Mubarak Ishaq Umar, Wong, Hei Yuen, Seng, Zijing, Xie, Yingpeng, Zhang, Yingchao, Yang, Liang, Kwok, Chun Kit, Deng, Xin
• Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; RNA G-quadruplexes (rG4); Bacteria
• Online Access: https://hdl.handle.net/10356/147329
• Institution: Nanyang Technological University

Guanine (G)-rich sequences in RNA can fold into diverse RNA G-quadruplex (rG4) structures to mediate various biological functions and cellular processes in eukaryotic organisms. However, the presence, locations, and functions of rG4s in prokaryotes are still elusive. We used QUMA-1, an rG4-specific...