Human cells can adaptively evolve to hypomorphic mutations in an essential gene of the nuclear pore complex

Adaptive evolution in response to cellular stress is a critical process implicated in a wide range of core biological and clinical phenomena, including emergence of drug resistance. While it is now widely accepted that single-celled organisms can rapidly adapt to selective pressure, we still lack un...

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書目詳細資料
主要作者: Targa, Altea
其他作者: Koh Cheng Gee
格式: Thesis-Doctor of Philosophy
語言:English
出版: Nanyang Technological University 2021
主題:
在線閱讀:https://hdl.handle.net/10356/147875
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