Carbene-catalyzed N,N-nucleophilic activation of thioureas for access to pyrimidinthione derivatives
An N-heterocyclic carbene-catalyzed [3+3] cycloaddition reaction of acylthioureas with ynals is reported. Both N atoms in the thiourea substrate are activated as nucleophiles and incorporated inside the ring system of the product. Pyrimidinthione derivatives bearing various substituents and substitu...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/148229 |
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| Institution: | Nanyang Technological University |
| Language: | English |