Defective ribosomes activate ribosome-associated quality control pathway

Maintaining cellular proteome integrity is crucial for normal cell functioning and survival as dysfunction to proteostasis gives rise to aging-related diseases. Cells have evolved a multitude of protein surveillance machineries to monitor the cytosol for aberrant proteins, including the ribosome-ass...

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Bibliographic Details
Main Author: Pek, Jonetta Shi Qi
Other Authors: Choe Young Jun
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/148577
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Institution: Nanyang Technological University
Language: English
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