Biological consequences of error during ribosome biogenesis

Rpl24, a eukaryotic 60S ribosomal protein, forms inter-subunit bridges. Lack of Rpl24 protein may weaken inter-subunit association, introducing problems during translation such as ribosome stalling. Ribosome stalling produces stalled polypeptides which accumulate to form toxic aggregates if undegrad...

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Bibliographic Details
Main Author: Tan, Xue Wei
Other Authors: Choe Young Jun
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2021
Subjects:
Online Access:https://hdl.handle.net/10356/152343
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Institution: Nanyang Technological University
Language: English