Reduced histone methylation associated with elevated body-mass index influences host susceptibility to severe dengue

• Main Author: Lee, Ariel Jia Ni
• Other Authors: Ruedl Christiane
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/148629
• Institution: Nanyang Technological University

Dengue virus infection causes dengue fever (DF), a mild febrile illness, that in some cases progresses into severe dengue (SD), a life-threatening complication. Accumulating evidence supports obesity as a risk factor for SD, but molecular events that lead to SD outcome remain unknown. Hence, to glea...