Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease

Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease

Structural and molecular myelination deficits represent early pathological features of Huntington disease (HD). Recent evidence from germ-free (GF) animals suggests a role for microbiota-gut-brain bidirectional communication in the regulation of myelination. In this study, we aimed to investigate th...

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Bibliographic Details
Main Authors: Radulescu, Carola I., Garcia-Miralles, Marta, Sidik, Harwin, Bardile, Costanza Ferrari, Nur Amirah Mohammad Yusof, Lee, Hae Ung, Ho, Eliza Xin Pei, Chu, Collins Wenhan, Layton, Emma, Low, Donovan, De Sessions, Paola Florez, Pettersson, Sven, Ginhoux, Florent, Pouladi, Mahmoud A.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Huntington Disease
White Matter
Online Access:https://hdl.handle.net/10356/148697
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/148697

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