Recognition of different base tetrads by RHAU (DHX36) : X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex
G-quadruplexes (G4) are secondary structures of nucleic acids that can form in cells and have diverse biological functions. Several biologically important proteins interact with G-quadruplexes, of which RHAU (or DHX36) - a helicase from the DEAH-box superfamily, was shown to bind and unwind G-quadru...
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Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/150541 |
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Institution: | Nanyang Technological University |
Language: | English |