Efficient, one-step, cascade synthesis of densely functionalized furans from unprotected carbohydrates in basic aqueous media

Condensation of unprotected carbohydrates with malononitrile or malonamide nitrile in basic aqueous media gave in one-pot densely functionalized polyhydroxyalkyl 2-amino-3-furanonitriles and polyhydroxyalkyl 2-amino-3-furanocarboxamides in excellent 84–98% yields. Disaccharides afforded novel furano...

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Bibliographic Details
Main Authors: Lambu, Mallikharjuna Rao, Judeh, Zaher M. A.
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/150625
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Institution: Nanyang Technological University
Language: English