Efficient, one-step, cascade synthesis of densely functionalized furans from unprotected carbohydrates in basic aqueous media
Condensation of unprotected carbohydrates with malononitrile or malonamide nitrile in basic aqueous media gave in one-pot densely functionalized polyhydroxyalkyl 2-amino-3-furanonitriles and polyhydroxyalkyl 2-amino-3-furanocarboxamides in excellent 84–98% yields. Disaccharides afforded novel furano...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
2021
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Online Access: | https://hdl.handle.net/10356/150625 |
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Institution: | Nanyang Technological University |
Language: | English |