A practical synthesis of densely functionalized pyrroles via a three-component cascade reaction between carbohydrates, oxoacetonitriles, and ammonium acetate

A practical synthesis of densely functionalized pyrroles via a three-component cascade reaction between carbohydrates, oxoacetonitriles, and ammonium acetate

A practical three-component reaction between unactivated carbohydrates, oxoacetonitriles, and ammonium acetate gave densely functionalized pyrroles in 75-96% yields. Disaccharides afforded novel pyrrolo-glycosides. This metal-free, Et3N-catalyzed cascade reaction proceeded with exclusive chemo-, reg...

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Bibliographic Details
Main Authors: Xia, Mengxin, Lambu, Mallikharjuna Rao, Tatina, Madhu Babu, Judeh, Zaher M. A.
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2022
Subjects:
Engineering::Chemical engineering
Carbohydrates
Mass Spectrometry
Online Access:https://hdl.handle.net/10356/159560
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/159560

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