Direct isolation of circulating extracellular vesicles from blood for vascular risk profiling in type 2 diabetes mellitus

• Main Authors: Tay, Hui Min, Leong, Sheng Yuan, Xu, Xiaohan, Kong, Fang, Upadya, Megha, Dalan, Rinkoo, Tay, Chor Yong, Dao, Ming, Suresh, Subra, Hou, Han Wei
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Medicine, Health and Life Sciences; Biomechanics; Nanotechnology
• Online Access: https://hdl.handle.net/10356/150958
• Institution: Nanyang Technological University

Extracellular vesicles (EVs) are key mediators of communication among cells, and clinical utilities of EVs-based biomarkers remain limited due to difficulties in isolating EVs from whole blood reliably. We report a novel inertial-based microfluidic platform for direct isolation of nanoscale EVs (exo...