In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659

In vitro phosphodiesterase 10A (PDE10A) binding in whole hemisphere human brain using the PET radioligand [18F]MNI-659

Highly specific and sensitive biomarkers for pathologies related to dysfunctions in the basal ganglia circuit are of great value to assess therapeutic efficacy not only clinically to establish an early diagnosis, but also in terms of monitoring the efficacy of therapeutic interventions and decelerat...

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Bibliographic Details
Main Authors: Svedberg, Marie M., Varnäs, Katarina, Varrone, Andrea, Mitsios, Nicholas, Mulder, Jan, Gulyás, Balázs, Beaumont, Vahri, Munoz-Sanjuan, Ignacio, Zaleska, Margaret M., Schmidt, Christopher J., Halldin, Christer, Mrzljak, Ladislav
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Autoradiography
Phosphodiesterase 10A
Online Access:https://hdl.handle.net/10356/151071
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/151071

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