Development of long duration releasing liposomes for prolonged content release in dental care applications

• Main Author: Chong, Jian Rong
• Other Authors: Hirotaka Sato
• Format: Thesis-Master by Research
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Engineering::Nanotechnology; Engineering::Chemical engineering
• Online Access: https://hdl.handle.net/10356/151543
• Institution: Nanyang Technological University

In this study, we report the alkali-encapsulating thermosensitive liposomes (Tris-Lipo) using DPPC/SA/PEG-DSPE (9/1/0.06, molar ratio) to enable environment pH regulation by sustained continuous cargo release at endogenous temperatures of 36.5oC. Tris-Lipo successfully neutralized the environmental...