Anti-inflammatory potential of simvastatin loaded nanoliposomes in 2D and 3D foam cell models

• Main Authors: Rakshit, Moumita, Darwitan, Anastasia, Muktabar, Aristo, Das, Prativa, Nguyen, Luong T. H., Cao, Ye, Vizetto-Duarte, Catarina, Tang, Jinkai, Wong, Yee Shan, Venkatraman, Subbu, Ng, Kee Woei
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Spheroid; Liposome
• Online Access: https://hdl.handle.net/10356/152176
• Institution: Nanyang Technological University

Atherosclerosis is a multifactorial disease triggered and sustained by risk factors such as high cholesterol, high blood pressure and unhealthy lifestyle. Inflammation plays a pivotal role in atherosclerosis pathogenesis. In this study, we developed a simvastatin (STAT) loaded nanoliposomal formulat...