An evolutionary and genomic approach to understand tumor evolution in hepatocellular carcinoma

• Main Author: Kaya, Arife Neslihan
• Other Authors: Mu Yuguang
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences::Genetics; Science::Medicine::Computer applications
• Online Access: https://hdl.handle.net/10356/152380
• Institution: Nanyang Technological University

Hepatocellular carcinoma (HCC) is one of the deadliest cancer types with diverse etiological factors across the world and very limited treatment options. Although large-scale genomic and transcriptomic studies have been conducted in different cohorts, an integrative analysis of HCC genomes and the e...