Functional and mechanistic studies on engineered antibodies that engage TRIM21

• Main Author: Chin, Wen Jie
• Other Authors: Julien Lescar
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/152476
• Institution: Nanyang Technological University

Depending on their state of maturation, dendritic cells (DCs) might initiate immune suppression or immune activation in DC-targeted therapies. In cases where immune activation is desired, adjuvants are often co-administered to augment the immune response. But adjuvants that rely on the use of pathog...