New route to macrocycles : synthesis of macrocycle via McMurry coupling
Named after its discoverer, John McMurry, McMurry coupling involves reductive dimerization of carbonyl compounds to yield olefins on treatment with low-valent titanium reagent. In this project, this mechanism had been adopted in order to synthesize an interesting macrocycle molecule. A TiCl4/Zn re...
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sg-ntu-dr.10356-153212023-03-04T15:38:58Z New route to macrocycles : synthesis of macrocycle via McMurry coupling Fan, Huiyi Andrew Clive Grimsdale School of Materials Science and Engineering DRNTU::Science::Chemistry::Organic chemistry::Polymers Named after its discoverer, John McMurry, McMurry coupling involves reductive dimerization of carbonyl compounds to yield olefins on treatment with low-valent titanium reagent. In this project, this mechanism had been adopted in order to synthesize an interesting macrocycle molecule. A TiCl4/Zn reagent system was employed. Isophthaloyl chloride had first undergone Friedel-Crafts acylation with octyl benzene. The diketone formed from acylation was the precursor for the McMurry coupling reaction. Bachelor of Engineering (Materials Engineering) 2009-04-27T07:51:22Z 2009-04-27T07:51:22Z 2009 2009 Final Year Project (FYP) http://hdl.handle.net/10356/15321 en 52 p. application/pdf |
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DRNTU::Science::Chemistry::Organic chemistry::Polymers Fan, Huiyi New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| description |
Named after its discoverer, John McMurry, McMurry coupling involves reductive dimerization of carbonyl compounds to yield olefins on treatment with low-valent titanium reagent.
In this project, this mechanism had been adopted in order to synthesize an interesting macrocycle molecule. A TiCl4/Zn reagent system was employed. Isophthaloyl chloride had first undergone Friedel-Crafts acylation with octyl benzene. The diketone formed from acylation was the precursor for the McMurry coupling reaction. |
| author2 |
Andrew Clive Grimsdale |
| author_facet |
Andrew Clive Grimsdale Fan, Huiyi |
| format |
Final Year Project |
| author |
Fan, Huiyi |
| author_sort |
Fan, Huiyi |
| title |
New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| title_short |
New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| title_full |
New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| title_fullStr |
New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| title_full_unstemmed |
New route to macrocycles : synthesis of macrocycle via McMurry coupling |
| title_sort |
new route to macrocycles : synthesis of macrocycle via mcmurry coupling |
| publishDate |
2009 |
| url |
http://hdl.handle.net/10356/15321 |
| _version_ |
1759855048068694016 |