New route to macrocycles : synthesis of macrocycle via McMurry coupling

• Main Author: Fan, Huiyi
• Other Authors: Andrew Clive Grimsdale
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Polymers
• Online Access: http://hdl.handle.net/10356/15321
• Institution: Nanyang Technological University

Named after its discoverer, John McMurry, McMurry coupling involves reductive dimerization of carbonyl compounds to yield olefins on treatment with low-valent titanium reagent. In this project, this mechanism had been adopted in order to synthesize an interesting macrocycle molecule. A TiCl4/Zn re...