The genetic dissection of trisomy 21 and partial trisomy 21 cellular pathologies using induced pluripotent stem cells
Introduction: Down Syndrome (DS), caused by full or partial trisomy of chromosome 21 (T21 or pT21) presents with accelerated ageing, intellectual disability (ID) and Alzheimer’s disease (AD). The contributions of individual HSA21 gene overdoses to these features remain poorly understood. Methods: iP...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
| Published: |
Nanyang Technological University
2021
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/153265 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |