Cx43 mediates changes in myofibroblast contraction and collagen release in human amniotic membrane defects after trauma

• Main Authors: Costa, Eleni, Okesola, Babatunde O., Thrasivoulou, Christopher, Becker, David Lawrence, Deprest, Jan A., David, Anna L., Chowdhury, Tina T.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Abnormal Connexin Expression; Fetoscopic Access Sites
• Online Access: https://hdl.handle.net/10356/153774
• Institution: Nanyang Technological University

The wound healing capacity of the fetal membranes after spontaneous or iatrogenic membrane rupture is unclear. We examined the healing mechanisms in amniotic membrane (AM) defects after trauma. Traumatised human AM defects were cultured for 4 days. Markers for nuclear (DAPI), cell type (vimentin, αS...