Competitive ELISA for a serologic test to detect dengue serotype-specific anti-NS1 IgGs using high-affinity UB-DNA aptamers

• Main Authors: Matsunaga, Ken-Ichiro, Kimoto, Michiko, Lim, Vanessa Weixun, Thein, Tun-Linn, Vasoo, Shawn, Leo, Yee Sin, Sun, William, Hirao, Ichiro
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Biological Techniques; Diseases
• Online Access: https://hdl.handle.net/10356/153798
• Institution: Nanyang Technological University

Serologic tests to detect specific IgGs to antigens related to viral infections are urgently needed for diagnostics and therapeutics. We present a diagnostic method for serotype-specific IgG identification of dengue infection by a competitive enzyme-linked immunosorbent assay (ELISA), using high-aff...