Antibody germline characterization of cross-neutralizing human IgGs against 4 serotypes of dengue virus

• Main Authors: Pannamthip Pitaksajjakul, Surachet Benjathummarak, Chonlatip Pipattanaboon, Waranya Wongwit, Tamaki Okabayashi, Motoki Kuhara, Ryo Misaki, Kazuhito Fujiyama, Pongrama Ramasoota
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33279

Dengue virus (DENV), a re-emerging virus, constitutes the largest vector-borne disease virus, with 50-100 million cases reported every year. Although DENV infection induces lifelong immunity against viruses of the same serotypes, the subsequent infection with the heterologous serotypes can cause mor...