Human single-chain variable fragment antibody expressed in E. coli with optimal in vitro cross-neutralizing and no enhancing activity

• Main Authors: Surachet Benjathummarak, Chonlatip Pipattanaboon, Khwanchit Boonha, Waranya Wongwit, Pongrama Ramasoota, Pannamthip Pitaksajjakul
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45005
• Institution: Mahidol University

© 2018 International Alliance for Biological Standardization Single chain fragment variable (scFv) is a small molecule antibody comprising of only the variable region of heavy and light chain responsible for antigen binding. For dengue disease, the Fc region of antibody molecule was reported to be i...