Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS
Itaconic acid is produced by immune responsive gene 1 (IRG1)-coded enzyme in activated macrophages and known to play an important role in metabolism and immunity. In this study, mechanism of itaconic acid functioning as an anti-inflammatory metabolite was investigated with molecular biology and immu...
Saved in:
Main Authors: | Zhu, Xiaoyang, Guo, Yangyang, Liu, Zhigang, Yang, Jingyi, Tang, Huiru, Wang, Yulan |
---|---|
Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2021
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/153799 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Actinomycins Produced by Streptomyces lichenis LCR6-01T and its Antibacterial Activity
by: Pawina Kanchanasin, et al.
Published: (2020) -
Pyruvate kinase regulates the pentose-phosphate pathway in response to hypoxia in mycobacterium tuberculosis
by: Zhong, Wenhe, et al.
Published: (2021) -
Bombyx mori transferrin: Genomic structure, expression and antimicrobial activity of recombinant protein
by: Yun, E.-Y., et al.
Published: (2014) -
Nanosystems for immune regulation against bacterial infections: a review
by: Zhang, Xiaodong, et al.
Published: (2022) -
Emerging Role for MAIT Cells in Control of Antimicrobial Resistance
by: Leeansyah, Edwin, et al.
Published: (2022)