LRG1 promotes metastatic dissemination of melanoma through regulating EGFR/STAT3 signalling

• Main Authors: Kwan, Yuet Ping, Teo, Melissa Hui Yen, Lim, Jonathan Chee Woei, Tan, Michelle Siying, Rosellinny, Graciella, Wahli, Walter, Wang, Xiaomeng
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Leucine-Rich α-2-Glycoprotein-1; Melanoma
• Online Access: https://hdl.handle.net/10356/153832
• Institution: Nanyang Technological University

Although less common, melanoma is the deadliest form of skin cancer largely due to its highly metastatic nature. Currently, there are limited treatment options for metastatic melanoma and many of them could cause serious side effects. A better understanding of the molecular mechanisms underlying the...