Elevation of a Novel Angiogenic Factor, Leucine-Rich- 2-Glycoprotein (LRG1), Is Associated With Arterial Stiffness, Endothelial Dysfunction, and Peripheral Arterial Disease in Patients With Type 2 Diabetes

• Main Authors: Pek, Sharon L. T., Tavintharan, S., Wang, Xiaomeng, Lim, Su Chi, Woon, Kaing, Yeoh, Lee Ying, Ng, Xiaowei, Liu, Jianjun, Sum, Chee Fang
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2015
• Subjects: Type 2 diabetes; Leucine-rich-α2-glycoprotein (LRG1)
• Online Access: https://hdl.handle.net/10356/80821; http://hdl.handle.net/10220/38882
• Institution: Nanyang Technological University

Increased arterial stiffness and endothelial dysfunction are associated with peripheral arterial disease (PAD). Leucine-rich-α2-glycoprotein (LRG1) is a proangiogenic factor involved in regulation of the TGFβ signaling pathway. - See more at: http://press.endocrine.org/doi/10.1210/jc.2014-3855#sthas...