Antimicrobial effect of a novel chitosan derivative and its synergistic effect with antibiotics

• Main Authors: Si, Zhangyong, Hou, Zheng, Vikhe, Yogesh Shankar, Thappeta, Kishore Reddy Venkata, Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Li, Peng, Zhu, Yabin, Pethe, Kevin, Chan-Park, Mary B.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering::Polymers and polymer manufacture; Antibacterial; Chitosan Derivatives
• Online Access: https://hdl.handle.net/10356/153841
• Institution: Nanyang Technological University

Cationic polymers are promising antibacterial agents since they have a low propensity for bacteria to evolve resistance, but they usually have low biocompatibility due to their hydrophobic moieties. Herein, we report a new biodegradable and biocompatible chitosan-derived cationic antibacterial polym...