High-density three-dimensional network of covalently linked nitric oxide donors to achieve antibacterial and antibiofilm surfaces

• Main Authors: Wang, Liping, Hou, Zheng, Pranantyo, Dicky, Kang, En-Tang, Chan-Park, Mary B.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering::Polymers and polymer manufacture; Healthcare-Associated Infections; Biomedical Device
• Online Access: https://hdl.handle.net/10356/153843
• Institution: Nanyang Technological University

Bacterial colonization on biomedical devices often leads to biofilms that are recalcitrant to antibiotic treatment and the leading cause of hospital-acquired infections. We have invented a novel pretreatment chemistry for device surfaces to produce a high-density three-dimensional (3-D) network of c...