Emerging evidence for kindlin oligomerization and its role in regulating kindlin function

• Main Authors: Bu, Wenting, Levitskaya, Zarina, Tan, Suet-Mien, Gao, Yong-Gui
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Kindlin; Oligomerization
• Online Access: https://hdl.handle.net/10356/154003
• Institution: Nanyang Technological University

Integrin-mediated cell-extracellular matrix (ECM) interactions play crucial roles in a broad range of physiological and pathological processes. Kindlins are important positive regulators of integrin activation. The FERM-domain-containing kindlin family comprises three members, kindlin-1, kindlin-2 a...