RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion

• Main Authors: Eichner, Hannes, Karlsson, Jens, Spelmink, Laura, Pathak, Anuj, Sham, Lok-To, Henriques-Normark, Birgitta, Loh, Edmund
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Factor-H-Binding; Capsule Biosynthesis
• Online Access: https://hdl.handle.net/10356/154008
• Institution: Nanyang Technological University

Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae and Haemophilus influenzae, are the major causative agents of bacterial meningitis, attributing to 200,000 deaths annually. These pathogens are of...